摘要
目的观察连续性肾脏替代治疗(CRRT)联合血液灌流(HP)对重度乌头碱中毒患者的疗效。方法对贵州医科大学附属医院重症医学科收治的1例重度急性乌头碱中毒患者,在洗胃、多器官支持基础上采用CRRT联合HP治疗,观察患者生命体征及其他相应变化。结果共进行4次CRRT(102h)及HP(8h),4d后患者病情逐渐稳定,各项生化指标逐渐转为正常,并成功停机拔除经口气管插管,顺利转出重症医学科。结论对于乌头碱中毒患者,尽早应用CRRT联合HP可有效清除体内毒物并快速纠正电解质及酸碱紊乱,提高乌头碱中毒患者抢救成功率。
Objective To observe the efficacy of continuous renal replacement therapy (CRRT) combined with hemoperfusion (HP) on patients with severe acute aconitine poisoning. Methods One patient suffered from severe acute aconitine poisoning was admitted into the Department of Critical Care Medicine of Affiliated Hospital of Guizhou Medical University, besides the gastric lavage and multi-organ supportive conventional therapies, CRRT combined with HP was given to the patient and his clinical data of life vital signs and other parameters were observed. Results After the patient underwent 4 episodes of CRRT (102 hours in total) and HP (8 hours in total) based on the conventional treatment, 4 days later, the disease situations were gradually stabilized, all of their parameters became gradually normal, the patient successfully weaned off from mechanical ventilation, the via mouth tracheal intubation was pulled out and the patient was transferred out of department of critical care medicine. Conclusion In the patient with acute aconitine poisoning, it is necessary to use CRRT combined with HP as early as possible, that can effectively eliminate the toxicant in the body and quickly correct the electrolytic and acid-base disturbances, so as the above combine method can improve the patient's prognosis and elevate the successful rescue rate.
作者
陈艳玲
李亮
沈锋
李伟
肖艳林
李贵美
陈黎
喻文艺
潘英
伍岳
Chen Yanling;Li Liang;Shen Feng;Li Wei;Xiao Yanlin;Li Guimei;Chen Li;Yu Wenyi;Pan Ying;Wu Yue(Department of Critical Care Medicine, Second People's Hospital of Guizhou Province, Guiyang 550001, Guizhou, China;Department of Critical Care Medicine, Affiliated Hospital of Guizhou Medical University, Guiyang 550004,Guizhou , China;Department of Critical Care Medicine, Second People's Hospital of Liuzhi County, Liupanshui 553400, Guizhou, China)
出处
《中国中西医结合急救杂志》
CAS
CSCD
北大核心
2018年第6期658-661,共4页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金
贵州省教育厅创新群体重大研究项目(黔教合ky 字〔2016〕034)
贵州省科技支撑计划项目(黔科合支撑〔2017〕2876)
贵州省留学人员择优资助科技创新项目(黔人项目资助合同〔2016〕19).
关键词
连续性肾脏替代治疗
血液灌流
乌头碱中毒
Continuous renal replacement therapy
Hemoperfusion
Aconitine poisoning
