摘要
随着生活水平提高,痛风已成为常见病,并呈现年轻化的趋势。痛风被证实与心血管疾病的发生密切相关,多项研究也表明痛风的心血管疾病共患率可达74%～91%。除了疾病本身,相关治疗药物,包括痛风治疗药物和心血管治疗药物也对这两类疾病有着交互作用。本文就痛风与心血管风险、痛风治疗药物的心血管获益与风险、心血管药物对痛风的影响等三方面进行讲述,以期加强临床对痛风的心血管风险的认识,对痛风和心血管疾病共患患者的诊治有所帮助。
The prevalence of gout have grown significantly in both developing and developed countries.More and more young people are affected.Gout has been proved to be associated with cardiovascular disease(CVD).This association is not coincidental as serial studies have shown that the combination rate of gout and CVD is between 74% and 91%.In addition to the two diseases,related medications,including gout medications and cardiovascular medications,also make the relation of gout and CVD complicated.The cardiovascular risk of gout,cardiovascular benefits and risks of gout medications and the effects of cardiovascular medications on gout are reviewed and discussed in this article,with the purpose to help recognize the cardiovascular risk when dealing with gout,and to help better clinical management of gout in patients with cardiovascular disease.
作者
赵力
邹和建
薛愉
ZHAO Li;ZOU He-jian;XUE Yu(Department of Rheumatologyp Huashan Hospital,Fudan University, Institute of Rheumatology,Immunology and Allergy,Fudan University,Shanghai 200040,China)
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2018年第12期1131-1135,共5页
Chinese Journal of Practical Internal Medicine
基金
国家自然科学基金项目(8167060028、81601396)
上海市申康发展中心专科疾病临床“五新”转化项目(16CR3012A).
关键词
痛风
高尿酸血症
心血管疾病
gout
hyperuricemia
cardiovascular disease
