摘要
目的:观察威枫骨科外洗散联合医用几丁糖关节腔内注射治疗膝关节骨性关节炎的临床疗效。方法:选取90例膝关节骨性关节炎患者为研究对象,随机分为3组,每组30例。其中,联合组使用威枫骨科外洗散联合医用几丁糖关节腔内注射治疗,外洗组单纯应用威枫骨科外洗散,几丁糖组单独选用医用几丁糖关节腔内注射。统计3组治疗前后的视觉模拟评分法(VAS)评分和WOMAC骨性关节炎指数评分,评估治疗效果。结果:治疗后,3组VAS评分均持续下降,差异均有统计学意义(P <0.01);联合组VAS评分均低于同期外洗组和几丁糖组,差异均有统计学意义(P <0.01)。治疗6周,3组WOMAC骨性关节炎指数评分均较治疗前提升,差异均有统计学意义(P <0.01);联合组WOMAC骨性关节炎指数评分高于外洗组和几丁糖组,差异均有统计学意义(P <0.01)。联合组临床疗效优于外洗组和几丁糖组,差异均有统计学意义(P <0.05)。结论:威枫骨科外洗散联合医用几丁糖关节腔内注射治疗膝关节骨性关节炎,可有效缓解疼痛,改善患者的膝关节功能,值得临床推广应用。
Objective:To observe the clinical effect of Weifeng Guke external washing powder combined with articular cavity injection of medical chitosan for knee osteoarthritis. Methods:Divided 90 cases of patients with knee osteoarthritis into three groups randomly,30 cases in each group. The combination group was treated with Weifeng Guke external washing powder combined with articular cavity injection of medical chitosan;the external washing group simply received Weifeng Guke external washing powder;the chitosan group was solely given articular cavity injection of medical chitosan. Observed the scores of visual analogue scale (VAS)and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) before and after treatment in the three groups,and evaluated the therapeutic effect. Results:After treatment,VAS scores in the three groups declined continuously,differences being significant (P<0.01). The VAS score in the combination group was lower than that in the external washing group and the chitosan group respectively at the same period,differences being significant(P<0.01). After six-week treatment,the scores of WOMAC in the three groups were improved when compared with those before treatment,differences being significant(P<0.01). The score of WOMAC in the combination group was higher than that in the external washing group and the chitosan group respectively,differences being significant(P<0.01). The combination group had better clinical effect than the external washing group and the chitosan group,differences being significant (P<0.05). Conclusion: The therapy of Weifeng Guke external washing powder combined with articular cavity injection of medical chitosan for knee osteoarthritis,can effectively alleviate pain and improve knee joint function of patients,which is worthy of clinical promotion and application.
作者
曾焘
唐剑邦
高大伟
陈亮
ZENG Tao;TANG Jianbang;GAO Dawei;CHEN Liang
出处
《新中医》
CAS
2018年第12期127-130,共4页
New Chinese Medicine
基金
国家中医药管理局基地科研专项(JDZX2015268)
关键词
膝关节骨性关节炎
威枫骨科外洗散
医用几丁糖
关节腔注射
疼痛
关节功能
Knee osteoarthritis
Weifeng Guke external washing powder
Medical chitosan
Articular cavity injection
Pain
Joint function
