摘要
目的:研究中医辨证治疗阴道炎的疗效观察及对患者微生态平衡的影响。方法:选取从2016年1月—2017年2月本院门诊检查确诊为阴道炎的患者共70例作为研究对象,采用随机数字表法随机均分为两组。对照组采取西医治疗,给予苯酰甲硝唑分散片;观察组采用中医辨证治疗,以中药汤剂内服外用方式治疗。观察记录两组患者治疗后的临床疗效、3个月复发率及两组不良反应的发生情况;并检测两组治疗前后细胞因子(IL-4、IL-6)水平。结果:观察组总有效率97.14%,明显高于对照组25.71%,差异有统计学意义(P<0.05);观察组3个月总复发率为8.57%;明显低于对照组25.71%,差异有统计学意义(P<0.05)。观察组治疗后不良反应发生率总计为2.86%,显著低于对照组20.00%,差异有统计学意义(P<0.05)。观察组治疗后临床症状(白带异常、外阴瘙痒、外阴疼痛、黏膜充血)消失时间明显短于对照组,差异有统计学意义(P<0.05)。观察组经治疗细胞因子IL-4、IL-6水平明显低于对照组,差异有统计学意义(P<0.05)。结论:中医辨证治疗阴道炎安全有效,能对患者微生态平衡起到良好的改善作用。
Objective:To observe the curative effect of TCM syndrome differentiation and treatment of vaginitis and its influence on the micro ecological balance of patients.Methods:A total of 70 patients with vaginitis diagnosed in our hospital from January 2016 to February 2017 were selected and randomly divided into two groups by random number table method.The control group was treated with western medicine,given Benzoylmetronidazole Dispersible Tablets.The observation group was treated with traditional Chinese medicine sydnrome differentation and treatment,oral and external use of Chinese medicine decoction treatment.The clinical efficacy,recurrence rate and adverse reactions in the two groups were recorded and compared between the two groups before and after treatment,and the levels of cytokines(IL-4,IL-6) before and after treatment in the two groups were detected and compared between the two groups before and after treatment,and the incidence of adverse reactions in the two groups was detected and compared between the two groups before and after treatment,and the levels of cytokines in the two groups were detected.Results:The observation group′s total efficiency was 97.14%,higher than the control group′s 25.71%.The difference was statistically significant(P<0.05).The observation group′s total recurrence rate was 8.57% which was significantly lower than the control group′s 25.71%.The difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 2.86%,which was significantly lower than that of the control group(20%),and the difference was statistically significant(P<0.05).The disappearance time of clinical symptoms(abnormal leucorrhea,pruritus vulvae,vulvar pain,hyperemia of mucous membrane) after treatment in observation group was significantly shorter than those in control group.The difference was statistically significant(P<0.05).The levels of cytokines IL-4 and IL-6 in the observation group were significantly lower than those in the control group and the diff
作者
哈虹
毛喆
HA Hong;MAO Zhe(The First Affiliated Hospital of Tianjin University of TCM,Tianjin 300110,China)
出处
《辽宁中医杂志》
CAS
2018年第12期2573-2576,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
天津市自然科学基金资助项目(033616323)
国家中医药管理局中医学术流派传承工作室建设项目(天津哈氏妇科流派传承工作室LPGZS2012-04)
关键词
中医辨证
阴道炎
微生态平衡
traditional Chinese medicine syndrome differentation
vaginitis
micro ecological balance
