摘要
为探讨1例左下肢深静脉血栓形成患者导管溶栓与抗凝治疗的合理性及药学监护过程,临床药师根据患者的基本情况、出凝血指标变化、溶栓与抗凝药物作用特点,协助临床医师制定溶栓与抗凝治疗方案,并对该病历进行疗效和不良反应的观察,结果显示患者在使用肝素联合尿激酶导管溶栓抗凝后效果不佳,改用比伐卢定导管溶栓后,活化部分凝血活酶时间达标,患者症状改善。患者的溶栓与抗凝症状得到有效的控制,治疗过程中未发生明显的药物不良反应,证明比伐卢定导管溶栓有效。
To investigate the rationality of a catheter thrombolysis and anticoagulant therapy in the left lower extremity in a patient with deep venous thrombosis pharmaceutical care was provided by clinical pharmacists according to the patient's basic situation,changes in coagulation parameters,thrombolytic and anticoagulant effects.Pharmacists assisted clinicians in making thrombolytic and anticoagulant treatment plans,and observed the efficacy and adverse reactions in the medical records.The patient had poor outcome after using heparin and urokinase catheters for thrombolytic anticoagulation and was given bivalirudin catheters.After the thrombolysis, activated partial thromboplastin time (APTT)reached the standard level and the patient's symptoms were improved. The thrombolytic and anticoagulant symptoms of the patient were effectively controlled.No obvious adverse drug reactions occurred during the treatment,demonstrating that bivalirudin catheter thrombolysis was effective.
作者
黄丽云
闫佳佳
HUANG Li-yun;YAN Jia-jia(The First Affiliated Hospital of Hainan Medical College,Haikou 570102;First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080)
出处
《中南药学》
CAS
2018年第12期1774-1777,共4页
Central South Pharmacy
关键词
临床药师
深静脉血栓
导管溶栓
抗凝治疗
clinical pharmacist
deep vein thrombosis
catheter thrombolysis
anticoagulant therapy
