摘要
自体富血小板血浆(PRP)是一种从自体血液中提取的富含高浓度血小板的血浆,激活后可释放大量参与创面修复的生长因子。目前临床研究表明PRP可应用于整形外科、口腔种植、颌面部及骨修复、心胸外科等领域,并可改善临床预后。PRP可促进血管生成及成纤维细胞增殖,因此PRP可促进创面愈合。然而,目前对PRP应用于烧伤创面愈合的临床研究仍较少,PRP在烧伤治疗中的应用尚未有统一的标准,并且PRP对烧伤创面的作用尚不完全清楚。本文将对PRP的应用是否对烧伤创面愈合及烧伤后瘢痕形成有效作一综述。
Autologous platelet-rich plasma (PRP)is plasma with high concentration of platelet extracted from autolo- gous blood.After activation,growth factors involved in wound healing are released from PRP.Current clinical investigations have demonstrated that the application of PRP seems to enhance the clinical outcome of plastic surgery,oral implantology,maxillofacial region and bone repair,and cardio-thoracic surgery. PRP can stimulate angiogenesis and promote fibroblast proliferation,therefore the application of PRP has shown good results in wound healing.However,up to date there is few current clinical researches on application of PRP on wound healing in burn patients.The application of PRP is not currently standardized,and the effects in burn wounds are poorly understood.This review is to determine if the application of PRP can outcome of burns and scar formation.
作者
杨思思
肖承志
Yang Sisi;Xiao Chengzhi(Department of Burns and Plastic Surgery,the General Hospital of PLA Tibet Military Area Command,Lhasa 850000,China)
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2018年第12期910-913,共4页
Chinese Journal of Burns
关键词
富血小板血浆
烧伤
伤口愈合
瘢痕
Platelet-rich plasma
healing
Cicatrix enhance the clinical Burns
Wound
