摘要
急性冠脉综合征(acute coronary syndromes,ACS)是指冠状动脉内不稳定的粥样斑块破裂或糜烂引起血栓形成所导致的心脏急性缺血综合征,是急诊科致命性胸痛的首要病因,包括ST段抬高型心肌梗死(STEMI)、非ST段抬高型心肌梗死(NSTEMI)和不稳定性心绞痛(UA),其中NSTE-MI与UA合称非ST段抬高型急性冠脉综合征(NSTE—ACS)[1-2]。ACS发病率高,致死致残率高,早期识别和早期治疗能明显降低病死率,改善远期预后。因此,对于这一类患者的早期、快速识别,是急诊科临床工作的重点。而在急诊科对ACS患者诊断中,心肌损伤标志物的检测是除临床症状及心电图以外的一项重要手段。
Acute coronary syndrome is the leading cause of fatal chest pain in the emergency department. The detection of troponin is one of the most important assays in the diagnosis of acute coronary syndrome,espe- cially for rapid rule-out of non-ST-elevation acute coronary syndrome (NSTE-ACS).With the development of de- tection technology,new generation point-of-care test cardiac troponin (POCT-cTn)and high-sensitivity cardiac troponin (hs-cTn)are more rapid and sensitive.POCT-cTn and hs-cTn may provide a clinically useful risk strati- fication tool for ACS.The early diagnosis of NSTE-ACS based on hs-cTn has been approved by domestic and foreign guidelines,at the same time,POCT-cTn has been widely used in emergency department.The combined application of the two detection assays may provide a new attempt for rapid and accuracy diagnosis of ACS in emer- gency department.
出处
《临床急诊杂志》
CAS
2018年第11期743-747,共5页
Journal of Clinical Emergency
