转化生长因子β_1及其受体与大肠癌
摘要
转化生长因子 β1(TGF β1)是人体多种组织细胞的生长调控因子 ,其对大多数正常细胞及上皮性肿瘤细胞具有生长抑制作用。转化生长因子 β1Ⅱ 型受体 (TβRⅡ)的表达减少是机体细胞逃逸TGF β1负调控作用从而发生癌变的一个重要改变。TGF β1及其受体的改变与大肠癌关系密切。
出处
《国外医学(生理病理科学与临床分册)》
2002年第1期19-22,共4页
Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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