摘要
目的 提高对卡氏肺囊虫肺炎 (PCP)的认识 ,探索电镜对卡氏肺囊虫肺炎的诊断意义以及预防PCP的方法。方法 通过对 95例肾移植术后受者中有发热、呼吸困难伴干咳的 1 6例患者作回顾性分析 ,X线胸片及肺部CT显示此 1 6例患者两肺弥漫性渗出性病变。其中 1 3例作支气管镜检 ,六胺银染色 (Jones)结合电镜活检确诊为卡氏肺囊虫肺炎。结果 选用复方磺胺甲基异恶唑(SMZco)治疗 ,1 5例康复 ,治疗过程中 4例血肌酐及胆红素轻度增高 ,停药后恢复正常 ,随访 2～ 1 2个月 ,PCP未复发。有 1例因呼吸衰竭死亡。结论 肾移植术后易罹患卡氏肺囊虫肺炎 ;PCP关键在于早期预防 ,早期诊断、早期治疗。
Objective To improve the understanding of pneumocystis carinii pneumonia (PCP) and investigate the role of electron microscopical examination in the diagnosis of PCP.Methods Sixteen out of 95 patients after renal transplantation who were diagnosed as having PCP were retrospectively analyzed.Results All 16 patients had fever, dyspnea and dry cough. X ray film and CT scan showed diffuse infiltrated lung disease. Bronchscopy was performed on 13 patients. Silver staining in combination with electron microscopical examination was used to confirm PCP. Sixteen patients were treated with SMZco intravenously. Fifteen patients recovered except for 1 patient died of respiratory failure. There were no recurrence during 2～12 months follow-up.Conclusions PCP is one of common complications after renal transplantation. Electron-mireroscopical examination is helpful for the diagnosis of PCP.
出处
《中华器官移植杂志》
CAS
CSCD
北大核心
2002年第2期78-80,共3页
Chinese Journal of Organ Transplantation
关键词
肾移植
卡氏肺囊虫肺炎
诊断
临床研究
治疗
Renal transplantation
Pneumonia, pneumocystis carinii
Diagnosis
