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RNA干扰技术在果蝇中的应用 被引量：2

RNA Interference in Drosophila
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摘要 RNA干扰是双链RNA特异诱导的转录后期基因沉默 .该技术随着不断完善而越来越被广泛地运用于果蝇的功能基因组研究上 ,双链RNA已经成为果蝇中功能基因的一个十分有效的抑制子 ,势必使RNA干扰技术成为研究果蝇体内基因功能的强有力的反向遗传学研究技术 . RNA interference is something of post transcriptional gene silencing, specifically mediated by double-stranded RNA. With the development of this technology and wider applications in the study of Drosophila, dsRNA has come to be a potent and efficacious inhibitor of gene activity in Drosophila. RNAi now promises to be a powerful reverse-genetic method to determine gene function in Drosophila.
作者 徐荣 陈峻 邓可京
机构地区 复旦大学生命科学院遗传学研究所
出处 《生物化学与生物物理进展》 SCIE CAS CSCD 北大核心 2002年第1期23-26,共4页 Progress In Biochemistry and Biophysics
关键词 RNA干扰 转录后基因沉默 果蝇 DICER酶 应用 RNA interference posttranscriptional gene silencing Drosophila Dicer
分类号 Q75 [生物学—分子生物学]
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参考文献12

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同被引文献46

  • 1朱华晨,许新萍,李宝健.一种简捷的Southern印迹杂交方法[J].中山大学学报（自然科学版）,2004,43(4):128-130. 被引量：8
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生物化学与生物物理进展
2002年 第1期

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