摘要
1983年1月至1988年6月,本院收治了1114例由细胞学或病理学确诊的广泛期小细胞肺癌。其中36例作单纯化疗,65例先化疗后放疗,12例先放疗后化疗,仅1例单纯放疗。化疗联合放疗可明显提高完全缓解率(P=0.000),全组总有效率为72.8%,1和2年生存率为40.4%和7.9%。在文中,我们对影响预后的因素进行了分析,结果表明,年龄、性别、上腔静脉压迫综合征、胸腔积液和声带麻痹对预后影响不大。
114 patients with extensive diseased small cell lung cancer diagnosed by cytology or patholo- gy were treated from January,1983 to June,1988.36 patients were treated by chemotherapy only, and 65 by radiotherapy followed by chemotherapy,and 12 by chemotherapy after radiotion and 1 patient was only given radiotherapy.This paper has shown that the chemo-radiotherapy evidently improved complete response rate of the first course.Total response rate was 72.8%,1 to 2 years survival rate being 40.4% and 7.9% respectively.In the paper an analysis of possiblc prognostic factors was carried out in patients with ED-SCLC.It was found that the factors,such as age,sex, SVC obstruction,pleural involvement,and nervus laryngeus recurrence paralysis,were of no prognostic significance.
出处
《实用肿瘤杂志》
CAS
北大核心
1991年第1期12-15,共4页
Journal of Practical Oncology