摘要
目的 本文运用食管测压法及食管运动图谱分析法对 5 6例以胸部不适 (胸痛、胸闷 )、反酸、烧心、吞咽困难或停滞感患者进行研究。方法 采用瑞典CTD Synectics公司生产的四通道连续灌注导管测压系统 ,导管径鼻腔插入食道 ,测定下食管括约肌压力 ,观察食管体部蠕动幅度、间期、传播速度和方向。结果 本病以老年多见。男、女之比为 2 .5∶1,5 6例中胃镜检查异常 2 3.2 1% ,X线检查异常 12 .5 % ,高压型食管下括约肌(LowerEsophagealSphincterLES) 8.93% ,低压型LES 5 3.5 7% ,正常型LES 37.5 0 % ,高压型蠕动 1.79% ,低压型蠕动 5 0 % ,失调型蠕动 48.2 1%。结论 LES异常及食管体部蠕动异常均为产生临床症状的主要因素之一 ,治疗以促胃肠动力药物加服质子泵抑制剂为主 ,疗效很佳。
Objective Fifty six patients with substernal discomfort (pain or pressure), regurgitation of acid, hearburn or intermittent esophageal is vatility were studied by esophageal manometry and analysis of esophageal motility patterns. Methods Four channels hydraulic Capillary Continuous Infusion System (manufactured by CTD Synectics Co.) was applied. The catheter was passed via the nose of the patient to esophagus to measure lower esophageal sphincter pressure (LESP) and to observe the peristaltic amplitude, interval, propagative velocity and direction of esophageal body. Results It was shown the disease low common was eldly. The ratio of male to female was 2.5∶1. Among 56 patients gastroscopic abnormality was 23.21%. X ray abnormality was 12.5%. The pressure patterns of LESP were hypertensive type accounting for 8.93%, hypotensive type 53.57% and normal type 37.5%. The esophageal motility disorders were hyperkinesia accounting for 1.79%, hypokinesia 50%, dyskinesia 48.21%. Conclusion It is suggested that LESP abnormality and esophageal motility disorders were the contributing factors of clinical symptoms. The most effective therapy should be gastrointestinal drugs cisapride in combination with acid suppression agents.
出处
《上海医学》
CAS
CSCD
北大核心
2001年第7期430-432,共3页
Shanghai Medical Journal
关键词
食管测压法
食管运动异常
胸痛
吞咽困难
Esophageal manometry
Esophageal motility disorders
Cheat pain
Dysphagia
