摘要
在一水硫酸氢钠存在下 ,异丁醇与对羟基苯甲酸发生酯化作用 ,高收率地合成了对羟基苯甲酸异丁酯。研究了一水硫酸氢钠用量、异丁醇用量和反应时间对羟基苯甲酸异丁酯收率的影响。当对羟基苯甲酸、异丁醇和硫酸氢钠的物质的量比为 1∶ 3∶ 0 .0 36,回流分水 7h时 ,酯收率达 99%
Isobutyl p hydroxybenzoate was synthesized in high yield by esterification of isobutyl alcohol with p hydroxybenzoic acid in the presence of sodium bisulfate monohydrate. The effects of the amount of sodium bisulfate monohydrate, the amount of isobutyl alcohol and reaction time on the yield of isobutyl p hydroxybenzoate have been investigated. The yield of the ester could reache 99.0% under amount of substance ratio of p hydroxybenzoic acid, isobutyl alcohol and sodium bisulfate were 1∶3∶0.036, refluxing and water segregation for 7h.
出处
《合成化学》
CAS
CSCD
2002年第1期68-70,共3页
Chinese Journal of Synthetic Chemistry