摘要
目的 :探讨青光眼滤过手术中使用透明质酸钠的临床效果。方法 :对 2 12例 (2 3 1眼 )各类青光眼行小梁切除术中前房内注入 1%透明质酸钠并保留 ,观察其并发症及效果 ,并抽出 5 0例随访平均 1 2年 ,此前 5 0例未使用透明质酸钠者为对照组 ,平均随访 1 1年。结果 :治疗组术后第一天前房积血发生率 4 2 % ,对照组 18% ;术后浅前房 5 6% ,对照组 3 6% ;脉络膜脱离 2 6% ,对照组14 % ;眼压 :术后 2 4小时平均 14 5mmHg ,对照组 6 7mmHg ,出院时眼压平均 11 3mmHg ,对照组成 12 5mmHg ;术眼视力 ;术后次日 74 4% ,出院时 87 9%的患者达到或超过术前 ,对照组则分别为 44 %及 68% ;远期效果实验组完全成功率 84% ,对照组 64 %。除出院时眼压两组差异无显著性外 (P <0 0 5 ) ,其它皆有显著性差异 (P <0 0 1)。结论 :青光眼滤过手术中使用透明质酸钠明显减少了并发症 。
Objective:To study the utility of sodium hyaluronate in the glaucoma filtering operation. Methods:Sodium hyaluronate was injected into anterior chamber in the trabeculectomy surgery for 212 patients (231 eyes) with glaucoma.The clinical effect was observed and recorded.50 of 212 patients were averagely followed up for 1 2 years.50 patients who were performed normal trabeculectomy and averagely followed up for 1～12 years were as control group. Results:The rate of hemorrhage in anterior chamber in treatment group was 4.2% and that of the control group was 16 7% (P<0 01).The rate of shallow anterior chamber in treatment group was 5 5% and that of the control group was 36 7% (P<0 01).The rate of visual acuity regain or better than before was 74.4% (second day) or 87 9% (fifth day) and that of the control group was 46% (P<0 01) or 70% (P<0 01).The intraocular pressure of treatment group was 14 5mmHg (second day).or 11 3mmHg (fifth day) averagely and that of the control group was 6.7mmHg (P<0 01) or 12 5mmHg (P>0 05).The successful rate of operation of treatment group was 984%,and that of the control group was 64% (P<0 01). Conclusions:Sodium hyaluronate using in filtering operation can decrease the complication and elevate the successful rate.
出处
《中国实用眼科杂志》
CSCD
北大核心
2002年第2期129-131,共3页
Chinese Journal of Practical Ophthalmology
