摘要
目的 :为了探讨胃食管反流病 (GERD)患者的呼吸系统症状与胃食管反流的关系。方法 :对 18例以呼吸系统症状为主要表现的GERD患者进行了食管测压和 2 4h食管pH值监测 ,并分析它们与症状的关系。另以92例呼吸系统症状的GERD患者作为对照。结果 :以呼吸系统症状为主要表现的GERD患者食管 2 4hpH监测的各项指标均高于无呼吸系统症状的GERD患者 (P <0 .0 1,0 .0 5 ) ;以呼吸系统症状为主要表现的GERD患者反流类型以卧位型为主 ,而无呼吸系统症状的GERD患者以立位型为主。以呼吸系统症状为主要表现的GERD患者咳嗽和哮喘与酸反流的症状指数均很高 ,分别为 85 .5± 14 .1(98.3～ 5 5 .4 )和 82 .0 2± 11.88(92 .9～ 5 6 .5 ) ,提示症状与酸反流密切相关。两组患者食管测压各项指标无显著差异。结论 :以呼吸系统症状为主要表现的GERD患者酸反流比普通GERD患者重 ,并且患者可以呼吸系统症状为唯一临床表现 ,而无食管症状 ,因此临床上极易误诊 ,我们在临床诊疗中要对这类患者给予高度重视。
Objective:To study the releationship between respiratory symptoms and gastroesophageal reflux (GER) in gastroesophageal reflux disease (GERD). Method:18 patients of GERD with respiratory symptoms as the primary presenting manifestation were examined by esophageal manometry and 24 h pH monitoring,The records were compared with those of GERD without respiratory symptoms (n=92).Results:①All data of esophageal 24h pH monitoring were higher in patients with GERD with respiratory symptoms as the primary presenting manifestation than those with GERD without respiratory symptoms ( P <0.01,0.05).②The type of GER was supine type predominate in GERD with respiratory symptoms as the primary prsesnting manifestation,but was upright type predominate in GERD without resiratory symptoms.③The Symptom index (SI) of cough and SI of asthma in GERD with respiratory symptoms as the primary presenting manifestation were 85.5±14.1(98.3～55.4) and 82.02±11.88(92.9～56.5) respectively,suggesting that there were correlation between respiratory symptoms and GER.④There were no significant difference in esophageal manometry between GERD with respiratory symptoms as the primary presenting manifestation and GERD without respiratory symptoms.⑤ Conclusions:The GER were more severe in GERD with respiratory symptoms as the primary presenting manifestation than GERD without respiratory symptoms.And respiratory symptoms could be as the sole presenting manifestation of GERD.So GERD with respiratory symptoms as the primary presenting manifestation were misdiagnosed often,we should think highly of such patients in our clinical diagnoses and treatment.
出处
《中国现代医学杂志》
CAS
CSCD
2002年第4期37-39,共3页
China Journal of Modern Medicine
关键词
胃食管反流病
咳嗽
哮喘
食管测压
PH监测
Gastroesophageal Reflux Disease
Cough
Asthma
Esophageal Manometry
Esophageal 24h pH Monitoring
