摘要
目的 :研究验方祛癣洗剂及其拆方对致病性浅部真菌的抑菌试验 ,以此论症方剂中的中药有协同增效作用。方法 :采用试管内药基法 ,分别测定祛癣洗剂中各单味中草药及其组成的三个不同方剂对我国南方常见的十种致病性浅部真菌的抑菌试验。结果 :祛癣洗剂组方中的十种中药有不同的抑菌谱 ,其抑菌MIC >18%～ 39% ,全部对白念珠菌无抑菌效果 ,组成的三种不同方剂 ,抑菌MIC分别为 11 2 5 %、6 2 5 %、10 0 %。结论 :方剂中的各药有协同作用 ,同浓度比较 ,方剂的抗菌谱及抑菌MIC优于单味中药 ,而随着组成的改变 ,不同的方剂抑菌的MIC也随着改变。
Studying antimycotic action of Quxuan lotion (QXL)and its Ingredients in vivo, we determined the minimum inhibitory concentrations (MIC) of each Chinese medicine in QXL and three different composition of the prescription, which against the ten different kind of fungi that caused the Dermatoses commonly in south china. Results indicate that prescription, ten Chinese medicines, had different antibiogram. The MIC was over 18%～39%. All of them couldn't against Candida albicans. The MIC of the three Chinese medicines of the prescription was 11.25%, 6.25% and 10.0%, respectively. Every Chinese medicine of the prescription had synergy action. On the same concentration, both MIC and antibiogram comparison, the prescription was better than each Chinese medicine of the prescription.
出处
《中国实验方剂学杂志》
CAS
2001年第6期19-20,共2页
Chinese Journal of Experimental Traditional Medical Formulae
基金
广东省中医药管理局科研基金No:983 90
