摘要
目的 :评价人类巨细胞病毒与肺癌的关系。方法 :对 6 0例原发性肺癌和 2 0例肺良性疾病的病理标本采用PCR扩增后电泳判断人类巨细胞病毒DNA的检测率。结果 :肺癌组人类巨细胞病毒DNA的检测率明显高于肺良性疾病组。结论 :人类巨细胞病毒感染与肺癌的发生有关 。
Abstract: To study the relationship between HCMV infection and lung Carcinoma. Methods: HCMV DNA sequence were detected in samples from 60 lung cancer patients and 20 patients with pulmonary diseases by polymerase chain reaction. Results: The positive rate of HCMV DNA sequence from lung cancer specimens was 23.33% , and none of specimens from 20 benign diseases gained positive results. The positive of the squamous cell carcinomas and adenocarcinomas were 22.22%, 26.32% respectively. Conclusion: HCMV infection may be one of the causes of lung carcinoma.
出处
《武汉大学学报(医学版)》
CAS
2001年第4期364-366,共3页
Medical Journal of Wuhan University
关键词
聚合酶链反应
巨细胞病毒感染
肺肿瘤
病因学
polymerase chain reaction
cytomegalovirus infection
lung neoplasms/ET