摘要
目的 探讨腹膜透析（ＰＤ）对重症急性出血坏死性胰腺炎（ＡＨＮＰ）诱发组织器官损害的保护作用。方法３４例 ＡＨＮＰ患者随机分为ＰＤ治疗组（２１例）和对照组（１３例），对照组采用常规综合治疗方式，ＰＤ治疗组除进行常现综合治疗外，还迸行间歇性腹膜透析（ＩＰＤ）治疗。两组均同时监测血ＴＮＦ－α、ＩＬ－β及血、尿淀粉酶水平，并行血、尿液、大便及透出液常规检查，以及观察肝、肾、心、脑等脏器功能。结果ＰＤ治疗组对脏器组织的保护作用优于对照组，可改善体内炎症状态，患者病死率（１４．３％）较对照组（３８．５％）低，平均住院天数（２０ ４±６．３）亦低于对照组（２９．７±１０．４）．结抡 腹膜透析对重症ＡＨＮＰ诱发的组织器官的损害具有保护作用。
Objective To explore the protective effects of peritoneal dialysis on tissue and organ damage induced by acute hemorrhagic necrotic pancreatitis (AHNP) . Methods Thirty-four AHNP patients were randomly divided into PD group ( n = 21) and control group (n=13). Control group was treated with conventional therapy, while PD group was treated with conventional therapy companied by intermittent peritonea] dialysis (IPD). Urinary and serum amylase, the plasma levels of TNF and IL-1, faecal occult blood test and serum leucocyte were examined. Functions of brain, kidney , liver and heart were observed. Results The protective effect was better in PD group than that in normal group (P<0.05). The survival rate was hihger and the number of hospitalization day decreased in PD group than those in normal group. Conclusion Peritoneal dialysis has a significant protection against tissue and organ damage induced by acute hemorrhagic necrotic pancreatitis.
出处
《中华肾脏病杂志》
CAS
CSCD
北大核心
2001年第6期369-371,共3页
Chinese Journal of Nephrology
关键词
腹膜透析
急性出血坏死性胰腺炎
器官
保护
Peritoneal dialysis
Acute hemorrhagic necrotic pancreatitis
Organ
Protection
