摘要
【目的】观察健脾补肾中药对恶性肿瘤化疗病人的白细胞减少症的作用。【方法】 71例患者随机分为治疗组与对照组 ,治疗组 37例 ,对照组 34例 ,治疗组于化疗日开始即予健脾补肾中药口服 ,每天 1剂 ,至化疗后第 2 8天止。对照组仅予化疗 ,不服中药。于化疗前 1天、化疗后第 7、 9、 12、 15、 18、 2 1天各复查血常规 1次。【结果】治疗组 37例患者共有 5例发生白细胞减少症 ,其中Ⅰ度 3例 ,Ⅱ度 1例 ,Ⅲ度 1例 ,发生率为 13.5 %。对照组 34例有 2 5例发生白细胞减少症 ,其中Ⅰ度 3例 ,Ⅱ度 13例 ,Ⅲ度 8例 ,Ⅳ度 1例 ,发生率为 73.5 % ,两组比较差异有显著性 (P <0 .0 1)。【结论】健脾补肾中药可有效预防化疗病人的白细胞减少症。
Objective To observe the effect of spleen-strengthening and kidney-reinforcing method on leukopenia in patients with malignant tumor after chemotherapy.Methods Seventy-one patients with malignant tumor were randomly allocated to Group A(n=37) and Group B (n=34).Group A was treated with spleen-strengthening and kidney-reinforcing herbal medicine and chemotherapy and Group B with chemotherapy only. The treatment course lasted 28 days.Blood routine examination was carried out before chemotherapy and on 7 th,9 th,12 th,15 th,18 th and 21 st day of chemotherapy.Results In Group A,5 cases of leukopenia were found, 3 in degree Ⅰ, 1 in degree Ⅱ and 1 in degree Ⅲ,the incidence being 13.5%; In Group B,25 cases of leukopenia were found, 3 in degree Ⅰ,13 in degree Ⅱ,8 in degree Ⅲ and 1 in degree Ⅳ, the incidence being 73.5%. There was significant difference between the two groups (P< 0.01).Conclusion Spleen-strengthening and kidney-reinforcing herbal medicine is effective in prevention of leukopenia in patients with malignant tumor after chemotherapy.
出处
《广州中医药大学学报》
CAS
2001年第4期295-297,共3页
Journal of Guangzhou University of Traditional Chinese Medicine
