摘要
目的 观察神经肽Y(NPY)与白癜风发病关系。方法 用放射免疫分析法测定 40例白癜风患者血浆NPY浓度 ,并与 2 3例正常对照者比较 ;同时测定其中的 2 5例患者白斑与非白斑部位皮肤组织液NPY浓度。结果 患者血浆NPY水平均比正常对照者显著增高 ;寻常型与节段型白癜风患者白斑部位皮肤组织液NPY浓度与非白斑部位相比无明显变化。结论 NPY与白癜风的发病可能存在一定关系。
Objective To observe the relationship between neuropeptide Y and the pathogenesis of vitiligo.Methods Radial immune assay(RIA) was adopted to determine the plasma NPY levels in 40 patients with vitiligo,compared with that of 23 normal controls,and the NPY levels in tissue fluids from the involved and uninvolved skins in 25 patients were determined,too.Results The NPY levels in patients were higher than that in controls,and there were no significant differences in NPY levels between the involved and uninvolved skin tissue fluids.Conclusion NPY may take roles in the pathogenesis of vitiligo.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2001年第5期295-296,共2页
The Chinese Journal of Dermatovenereology
