摘要
目的 :观察配戴角膜塑型镜 (Orthokeratology)后 1年的角膜内皮细胞、角膜厚度的变化。方法 :观察随访了 1年的OK镜治疗者 43例 83眼 ,根据近视屈光度分为 2组 ,Ⅰ组 ( <5 0D) 2 2例 46眼 ;Ⅱ组 (≥ 5 0D) 2 1例 37眼。运用非接触式角膜内皮显微镜、角膜测厚仪分别检查角膜内皮细胞及厚度的变化 ;同时运用Eyesys角膜地形图及A超分别检查角膜曲率及眼轴的变化并记录视力及屈光度的改变。结果 :戴镜后 1年所有患者裸眼视力增加、屈光度减少、角膜中央曲率变平 (P <0 0 0 1)。两组角膜内皮细胞均有轻度减少 (P<0 0 5 ) ,两组内皮细胞损失量对比无显著性差异 (P >0 0 5 )。两组角膜中央区厚度均轻度变薄 (P <0 0 5 ) ,而两组厚度变化量比较在统计学上无显著性差异 (P >0 0 5 )。结论 :角膜塑型术对降低近视屈光度效果明显 ,但长期配戴有可能造成角膜内皮细胞及厚度轻度减少 。
Objective:To observe the changes in corneal endothelium and the thickness after 1 year management of orthokeratology. Methods:83 eyes of 43 patients who had worn orthokeratology lenses for 1 year were divided into two groups according to their diopters of myopia.In group I the refractive error was less than 5.0D(22 patients,46eyes),group II no less than 5 0D(21 patients,37eyes).The changes after 1 year lenses wearing in the corneal endothelium and thickness were measured with noncontact specular microscope and ultrasonic pachymeter,respectively.Changes in radius and axial eye length were also measured with Eyesys system and A mode ultrasonic tool,respectively.Unaided acuity and refractive changes were recorded. Results:After 1 year wearing,the density and thickness of endothelial cells of two groups decreased statistically differently(P<0 05),and on the amounts of lost endothelial cells there had no significant differences between them(P>0 05).The improvements of unaided acuity,refraction and the central corneal radius were statistically significance(P<0 001). Conclusions:Orthokeratology is effective on the correction of myopia.The central corneal endothelial cell density and thickness decreased slightly after 1 year treatment.
出处
《中国实用眼科杂志》
CSCD
北大核心
2002年第1期70-72,共3页
Chinese Journal of Practical Ophthalmology
关键词
角膜塑型术
角膜内皮细胞
角膜厚度
Orthokeratology,Corneal endothelium,Corneal thickness
