摘要
目的：探讨黄芪对主要中分子组分（ＭＭ）损伤心肌细胞的保护作用。方法：在培养的乳鼠心肌细胞中，用主要ＭＭＳ损伤组分（ＭＭＳⅡ）加入黄芪共同培养，观测心肌细胞搏动的频率和幅度，并测定ＬＤＨ释放量、苔盼兰摄取率。结果：黄芪组心肌细胞搏动的频率和幅度、ＬＤＨ释放量、苔盼兰摄取率不受ＭＭＳⅡ影响。结论：黄芪对ＭＭＳ损伤心肌细胞有明显的保护作用。
Objective: To study the protective role of Astragalus membranaceus on myocardical cells against damages caused by middle molecular substances(MMS). Methods: Both the main damaging element of MMS(MMS Ⅱ ) and astragalus membranaceus were added to cultured myocardical cells. Beating strength and rate of myocardical cells were observed. LDH and Trypan blue exclusion were also measured. Results: Beating strength and rate of myocardical cells, LDH and Trypan blue exclusion of cultured myocardical cells were not affected by MMS Ⅱ in astragalus membranaceus treated group. Conclusion: Astragalus membranaceus can protect myocardical cells from damage by MMSⅡ.
出处
《中国中西医结合肾病杂志》
2002年第1期16-17,共2页
Chinese Journal of Integrated Traditional and Western Nephrology
基金
湖北省卫生厅资助项目(No.97-252)
关键词
黄芪
中分子物质
尿毒症
心肌细胞
细胞培养
Astragalus membranaceus Middle Molecular substances Uremia Myocardical cells Cell culture
