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功能性消化不良24小时胃窦运动及胃电图改变 被引量:11

Changes of 24-hour gastric motility and myoelectric activity in patients with functional dyspepsia
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摘要 目的 研究功能性消化不良 (FD)患者 2 4h胃窦运动及胃电变化规律和不同临床分型特点。方法 用 2 4h胃窦十二指肠压力及胃电图联合检测仪对 2 0例健康对照者和 31例FD患者同时进行胃窦十二指肠压力及胃电图测定。结果 FD患者较健康人移行性复合运动 (MMC)周期数显著减少 ,Ⅰ相 +Ⅱ相时程显著延长 (P <0 .0 1) ;餐后FD患者胃窦收缩次数、收缩幅度及动力指数均明显低于健康人 (P <0 .0 5 ) ,但不同临床类型FD患者胃窦运动无明显差异。FD患者还存在明显胃电节律异常 ,运动障碍样型胃电节律紊乱及胃动过缓发生率较高 ,而溃疡样型及非特异型胃动过速发生率较高 (P <0 .0 5 )。结论 FD患者存在胃窦运动异常 ,但与FD临床分型无关。胃电图对FD患者的临床分型有一定意义。 Objective To investigate the changes of 24 hour gastric motility and myoelectric activity in patients with functional dyspepsia (FD) and to compare the differences of these changes among the different clinical types of FD. Methods 24 hour gastric and duodenal manometry combined with 24 hour electro gastrography was carried out in 31 patietns with FD and 20 normal controls. Results Compared with normal controls, patients with FD had less frequency and longer duration of migrating motor complex (MMC), and phase Ⅰ plus phase Ⅱ duration were also greatly increased ( P <0.01); After meal, the frequency and amplitude of contractions and the motility index of gastric antrum in patients with FD were much more decreased than those in normal controls ( P <0.05), while there were no differences of these changes among different clinical types of FD. Patients with dysmotility like type had higher incidence of gastric dysrhythm and bradygastria, while patients with ulcer like type and unspecific type had higher incidence of tachygastria ( P < 0.05). Conclusions Patients with FD had gastric antrum dysmotility but there were no differences among different clinical types. Electrogastrogram might play a role in clinical classification of FD.
出处 《中华消化杂志》 CAS CSCD 北大核心 2001年第9期537-539,共3页 Chinese Journal of Digestion
关键词 功能性消化不良 测压 移行性复合运动 胃电图 胃窦运动 Functional dyspepsia 24 hour manometry Migrating motor complex Electrogastrogram
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