摘要
目的 :观察术后病人应用吗啡行硬膜外腔持续恒注镇痛 (CEIA)以探讨其镇痛效果、副作用。方法 :72例ASAI Ⅱ级中下腹手术病人 ,按不同吗啡复合液将其分为两组 :Ⅰ组吗啡 10mg加生理盐水至 5 0ml,Ⅱ组 0 .12 5 %布比卡因 + 0 .2 5 %利多卡因 +吗啡 4mg,加生理盐水至 5 0ml。在注药后 2 4小时内分别观察下列指标 :心率、血压、呼吸频率、VAS以及恶心呕吐、瘙痒等副作用。结果 :心率、血压、呼吸频率以及恶心呕吐、瘙痒等副作用在两组病人中差异无显著意义 ,但Ⅱ组有 4例病人血压呈一过性下降 ,经对症处理后好转。第Ⅰ组病例在注药后第 4h、8h、2 4h镇痛效果明显优于第Ⅱ组。结论 :术后CEIA使用 10mg吗啡剂组 。
Objective:To study the psotoperative effects and side effects of different dosages of morphine in continuous epidural infusion on postoperative analyesia(CEIA).Methods:According to different postoperative analgesic methods,72 patients were randomly divided into two groups:morphine 10 mg(n=36,I group),0.125% bupivacaine+0.25% Lidocaine+morphine 4 mg(n=36,Ⅱ group).The following data were recorded in postoperative 24 hours:heart rate (HR),blood pressure(BP),respirative rate(RR),VAS,and the postoperative nausea and vomiting,pruritus.Results:Nostatistical differences were found in HR,BP,RR,and side effects between two groups.4 patients of Ⅱ group had ever greatly decreased in blood pressure.The improvement of pain was more in Ⅰ group than Ⅱ group.Conclusion:Morphine 10 mg was an effective and safer analygesic regime for continuous epidural infusion on postoperative analgesia.
出处
《中国民政医学杂志》
2001年第4期225-226,共2页
Medical Journal of Chinese Civil Administration
