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亚急性脊髓联合变性12例临床分析 被引量:1

A clinical analysis of 12 patients with subacute combined degeneration
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摘要 目的 探讨和评价亚急性脊髓联合变性 ( SCD)的临床特征及相关辅助检查的诊断价值。方法 回顾分析 1 2例 SCD患者的临床资料。结果 本组患者多种病因 ,肢体感觉异常和深感觉减退是 SCD最常见症状和体征 ,大部分伴有周围神经损害及植物神经损害。结论 电生理检查对 SCD的诊断有重要作用 ,体感诱发电位有很高的敏感性 。 Objective To investigate and evaluate the clinical character of subacute combined degeneration and the diagnostic values of concerned examinations.Methods A retrospective analysis of 12 cases of subacute combined degeneration was presented.Results The results showed that there were many causes for subacute combined degeneration.Parasthesias of the limbs and diminished vibration and position sensations were the most common symptoms and signs.Most of them were accompanied by peripheral nerve injury and autonomic nerve injury.Conclusions The examinations of electrophysiology could play an important role in the diagnosis of subacute combined degeneration.Somatosensory evoked potentials had high sensitivity and magnetic resoname imaging had no specific changes in the spinal cords.
出处 《北京医学》 CAS 北大核心 2001年第6期338-340,共3页 Beijing Medical Journal
关键词 亚急性脊髓联合变性 维生素B12缺乏 诱发电位 诊断 临床表现 病例分析 Subacute combined degeneration VitaminB 12 deficiency Somatosensory evoked potential
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  • 1史玉泉,实用神经病学,1998年,310页 被引量:1

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  • 1Healton EB, S avage DG, Brust J, et al. Neurologic aspects of cobalamin deficiency. Medicine, 1991, 70:229 - 245. 被引量:1
  • 2Reynolds EH, Bothglieri T, Laundy M, et al. Subacute combined degeneration with high serum vitamin Bt2 level and abnormal vitamin B12 binding protein. Arch Neurol, 1993, 50:739 - 742. 被引量:1
  • 3Fritschi J, Sturzenegger M. Spinal MRI supporting myelopathic origin of early symptoms in unsuspected cobalamin deficicy. Eur Neurol, 2003, 49 : 146 - 150. 被引量:1

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