摘要
猪水肿病 (ED)由肠毒血症大肠杆菌 (ETEEC)引起。在母源抗体 Ig A下降、饲料中蛋白质含量过高、缺硒和过食等诱因的刺激下 ,猪肠道内大肠杆菌迅速繁殖 ,依靠定植因子粘附到肠粘膜细胞上 ,并产生 SL T- IIe毒素。 SL T- IIe是一种热不稳定蛋白质 ,它能与血管内皮细胞和平滑肌细胞上的受体结合 ,阻碍细胞内蛋白质合成 ,造成血管损害而致水肿。
Edema disease of swine (ED) is caused by enterotoxaemic E. coli (ETEEC). Stimulated by the pathogenies such as the reduction of maternal derived antibody IgA, high protein diet, Se deficiency, and excessive intake, E. coli in intestines multiply rapidly, adhere to the cells of intestinal mucous membrane, and produce SLT IIe. SLT IIe is a heat labile protein, and can bind to the receptors of the endothelial and smooth muscle cells of blood vessels, and inhibit protein synthesis in the target cells, and cause vascular lesions finally resulting in edema.
出处
《动物科学与动物医学》
2001年第6期38-41,共4页
Animal Science & Veterinary Medicine
