摘要
目的:研究地高辛血药浓度(CDGX)>2.4 ng·ml-1在中毒诊断中的作用及影响因素。方法:对118例CDGX>2.4 ng·ml-1住院病例进行分析。结果:80.5％CDGX>2.4 ng·ml-1患者的BUN>7.2 mmol·L-1,合并使用使CDGX升高药物的占总例数的55.7％,ECG检查示房室传导阻滞的占29.7％,室性早搏占27.1％。结论:CDGX>2.4 ng·ml-1是多种因素共同影响的结果,包括合并用药、肾功能损害等因素,对地高辛中毒的诊断应将血药浓度监测结果与临床症状相结合。
Objective: To study the effects of CDGX>2.4 ng·mi-1 in diagnosing digoxin toxication and the clinical related factors influencing th CDGX. Methods: To analysis 118 cases of in-patients with CDGX >2.4 ng·ml-1. Results: The cases, whose BUN were over7.2mol·L1, acounted for 80.5% of total studied cases, the cases, whose Cdgx were increased because using simutaneously the other drugs, acounted for 55.7% , the atrioventricular block proved by ECG 29. 7% , the ventricular premature contraction 27.1 %. Conclusion: CDGX>2.4 ng·ml-1 is a common result induced by multi-factors including in combination with medications, kidney injury, and so on. The diagnosis of digoxin toxication should be made by the results of blood concentration monitoring in combination with the clinical symptoms.
出处
《中国药师》
CAS
2001年第5期369-370,共2页
China Pharmacist
