摘要
目的 :探讨血清CYFRA2 1- 1、CA50 、CEA变化对诊断肺癌的临床价值。方法 :应用放射免疫法对 186例肺癌患者进行血清CYFRA2 1- 1、CA50 、CEA联合检测。结果 :肺癌组患者血清CYFRA2 1- 1、CA50 、CEA检测水平明显高于正常对照组 (P <0 .0 1)、三项联合 (CYFRA2 1- 1+CA50 +CEA)检测的敏感性和准确性最高 ,分别为 :91.4 %、86.2 % ,优于二项和单项检测。结论 :三项肿瘤标志联合检测可提高肺癌的早期诊断率 ,在病情检测方面可为临床提供有价值的资料。
Objective: To study the clinical value of the change of serum CYFRA 21-1,CA 50,CEA for the diagnosis of lung cancer. Methods: The serum levels of CYFRA 21-1,CA 50,CEA in 186 patients with lung cancer were simultaneously tested by the means of immunoradiometric assay. Results: The serum levels of CYFRA 21-1,CA 50,CEA in patients with lung cancer were significantly higher than those in the normal controls (P<0.01). The sensitivity and accuracy of combined test were the highest, which were 91.4% and 86.2%, respectively, more valuable than the test of one or two items only. Conclusions: The combined test of the three tumor markers can improve the diagnosis of lung cancer in early stage and provide valuable data for clinical evaluation for the disease progression.
出处
《山西中医学院学报》
2001年第2期28-29,共2页
Journal of Shanxi College of Traditional Chinese Medicine
