摘要
对72例月经周期正常的健康妇女,分别按月经周期的不同时间,取子宫内膜,以直接法制备染色体标本。结果表明,①子宫内膜中期分裂相,于月经周期的第5～10d即达高峰,持续到月经周期第16d;于周期第17～22d,分裂相明显减少;至月经第23d以后,内膜细胞的有丝分裂活动几近停止。②在正常月经周期的第14d左右可发生排卵,排卵后内膜初受孕酮影响的时间至少在排卵后36～48h,不会严重干扰中期分裂相的出现。③从子宫前壁或后壁内膜取材直接制备染色体标本进行比较,二者无显著性差异(P>0.05)。④所取组织量与获得中期分裂相数目间呈正相关,有极显著意义(P<0.01)。
Rapid preparation of chromosome specimens was carried out with human
endometrium. Samples were taken from 72 healthy women during their normal
menstrual cycles. The results showed that mitotic rate of the endometrial cells
approached its maximal level by day 5 and then stayed roughly constant to day
16, after which it began to drop remarkably until mitotic activity practically
ceased after day 22. The primary influence of progestorone, which occurred
36～48 hours after ovulation, did not interfere with the appearance of mitotic
metaphase. The number of karyotypes obtained showed no significant difference
between samples taken from the front wall and those from the back wall of the
uterine body (P>0.05). The size of the sample was positively correlated
with the number of karyotypes obtained (P<0.01).
出处
《青岛医学院学报》
1991年第2期87-91,共5页
Acta Academiae Medicinae Qingdao Universitatis
关键词
子宫内膜
染色体
月经
endometrium
chromosome
mitosis
menstruation
