摘要
目的 探讨脂蛋白 (a) ,氧化低密度脂蛋白与颈动脉粥样硬化 (AS)及脑梗塞间的关系。方法 对50例脑梗塞患者 ,32例高血压病患者及30例健康人进行颈动脉超声检查 ,同时测定血浆脂蛋白 (a)[LP(a)],氧化低密度脂蛋白 (OXLDL)浓度。结果 AS者LP(a)、OXLDL明显高于颈动脉超声阴性者 ;脑梗塞及高血压病患者斑块明显增加 ,斑块积分、斑块指数及LP(a)、OXLDL值明显增高 ,其中以脑梗塞患者增高尤为显著。结论 LP(a)和OXLDL异常能促进AS形成与脑梗塞的发病密切相关。
Objective To explore correlation between lipoprotein-a, oxidized low density lipoprotein with carotid artery atherosclerosis (AS) and cerebral infarction. Methods Ultrasonic examination was made on 50 Cerebral infarction cases, 32 hypertension cases and 30 healthy cases together with the detection of serum lipoprotein-a(LP-a), oxidized low density lipoprotein (OXLDL). Results LP-a and OXLDL in AS cases were higher than those of negative carotid ultrasound examination cases. They were also higher in hypertension and cerebral infarction cases than in healthy cases. Conclusion abnormal LP-a and OXLDL could induce AS, which was considered to have correlation with cerebral infarction.
出处
《浙江临床医学》
2001年第12期881-882,共2页
Zhejiang Clinical Medical Journal
