摘要
目的分析四年中自老年病房分离的426株葡萄球菌对抗生素的敏感率,以指导其治疗。方法利用全自动细菌分析系统测定15种抗生素的体外抗菌活性。结果老年患者葡萄球菌感染的致病菌以金黄色葡萄球菌为主,占87.1%;98.3%菌株产β-内酰胺酶,91.6%菌株属耐甲氧西林葡萄球菌,87.3%菌株耐三种以上不同种类抗生素。对万古霉素敏感率为100%,呋喃妥因为99.3%,其他抗生素的抗菌活性不高。结论万古霉素仍是老年患者耐甲氧西林葡萄球菌严重感染的选用药。
Objective To analyse the antibiotic susceptib ility of 426staphylococcus isolate s from the aged patients from1997to 2000.Methods 15kinds of antibiotic were tested by VITEK Auto Microbe System for their a ntimicrobial action.Results Most infections were induced by Stap hylococcus aureus,which accounted for 87.1%,98.3%of the total microbi al strains producedβ-lactamases,91.6%strains were Methicillin -Resistant Staphylococcu s aureus(MRSA)and 87.3%strains were resistant to three or more kinds of antibiotic.The susceptibilities to Vancomycin an d Nitrofurantoin were 100%and 99.3%,but the antibac-terial activities of other antibiotics were low.Conclusions Vancomycin is still proposed as a can didate drug for serious MRSA infection in the aged patients.[
出处
《老年医学与保健》
CAS
2001年第4期228-229,246,共3页
Geriatrics & Health Care
