摘要
目的:探讨甲基泼尼松龙对急性脑衰竭的治疗作用。方法;对入选的72例急性脑衰竭病人随机对照研究,甲基泼尼松龙组和对照组病人各36例。根据Glasgow-Pittsberg昏迷评分,对两组病人治疗前及治疗后7、14天的临床神经功能状况进行比较,评定临床效果。对比观察两组病人病死率及副作用发生情况。结果:治疗第7天甲基泼尼松龙组的昏迷评分明显高于对照组(P<0.05);甲基泼尼松龙对于全身性疾病所致的急性脑衰竭疗效显著优于颅内疾病所致者(P<0.001)。结论:甲基泼尼松龙对急性脑衰竭有显著治疗作用。
Purose:This study is to observe the effect of methylprednisolone on management of acute brain failure(ABF). Methods:72 cases of ABF patients were studied by comparison randomly. There were 36 cases in each of therapeutic and control groups. The neurologic outcome of all these patients pre-and 7、 14 days post-treat-ment was observed with Glasgow-Pittsberg scale, and occurrence of mortality and side effect. Results: The methylprednisolone group showed higher level of Glassgow-Pittsberg scale than the control group at 7 days after treatment( P <0.05). With methylprednisolone therapy, the clinical efficacy of the patients with general disease induced ABF was much more superion to that of acute cerebrovascular induced( P <0.001). Conclusions: The methy Iprednisolone could be beneficial to the treatment of ABF.
出处
《临床急诊杂志》
CAS
2001年第5期228-229,共2页
Journal of Clinical Emergency
