摘要
目的 对多歧沙参 Adenophora wawreana的根进行较系统的化学成分研究。方法 采用系统溶剂分离法和硅胶柱色谱法进行提取分离 ,用光谱法 (IR、1 HNMR、1 3 CNMR、MS等 )进行结构鉴定。结果 从石油醚提取部位分离得到 12个化合物 ,鉴定了其中 9个化合物的结构 ,它们分别为十六酸 - 3- β-谷甾醇酯 (β- sitosteryl hexade-canoate, )、十八酸 - 3- β-谷甾醇酯 (β- sitosteryl octadecanoate, )、α-香树脂醇乙酸酯 (α- am yrin acetate, )、羽扇豆烯醇乙酸酯 (lupeol acetate, )、羽扇豆烯酮 (lupenone, )、木栓酮 (friedelin, )、β-谷甾醇 (β- sitosterol, )、7α-羟基 -β-谷甾醇 (lkshusterol, )和胡萝卜苷 (daucosterol, )。结论 9个化合物均首次从本植物中分离得到 ,其中化合物 、 、 、 、
Object To study systematically on the chemical constituents of the roots of Adenophora wawreana Zahibr Methods The chemical constituents were extracted and isolated systematically with solvents and silica gel chromatography Their structures were determined on the basis of spectral data (IR, 1HNMR, 13 CNMR and MS) Results Twelve compounds were obtained, nine of them were identified as β sitosteryl hexadecanoate (Ⅰ), β sitosteryl octadecanoate (Ⅱ), α amyrin acetate (Ⅲ), lupeol acetate (Ⅳ), lupenone (Ⅵ), friedelin (Ⅶ), β sitosterol (Ⅸ), ikshusterol (Ⅹ) and daucosterol ( ⅩⅡ ) Conclusion All of them were obtained for the first time from A wawreana and compounds Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅶ were obtained for the first time from Adenophora Fisch
出处
《中草药》
CAS
CSCD
北大核心
2001年第11期964-966,共3页
Chinese Traditional and Herbal Drugs
基金
教育部高等学校博士学科点专项科研基金资助项目 No.95 0 10 2 3
关键词
多歧沙参
沙参属
化学成分
中药
Adenophora wawreana Zahlbr
Adenophora Fisch
chemical constituents
