摘要
目的 探讨AS2 O3 治疗急性早幼粒细胞白血病 (APL)的安全性。方法 对 36例用AS2 O3 治疗的APL患者的副反应进行了观察和护理。结果 常见副反应中 ,白细胞过多综合征发生率为 6 6 6 7%,胃肠道反应发生率为5 5 5 6 %;皮肤指 (趾 )甲改变发生率为 41 6 7%。性别、年龄及初治、复治因素对副反应发生无影响。结论 加强对患者的观察 ,及时做好心理护理 ,对提高砷剂的疗效和安全性有重要意义。
Objective To observe the safety of arsenic trioxide (AS 2O 3) in the treatment of acute promyelocytic leukemia (APL).Methods The clinical side effects in the treatment of 36.APL patients were observed and nursed carefully.Results In the clinical side effects,the rate of white blood cell increased syndrome was 66.67%,gastrointestinal symptoms was 55.56%,Skin roughness and pigmentation deposited symptoms was 41.67%.The factors such as age,sex,previously untreated case and relapase case cann't influnce the results.Conclution Strengthen the clinical observation and mental nursing improved the effectiveness and safety of AS 2O 3 in the treatment of APL.
出处
《实用护理杂志》
北大核心
2001年第12期6-8,共3页
Journal of Practical Nursing
