摘要
目的 :初治成人急性非淋巴细胞白血病 (AL L )治疗缓解率相关因素分析。方法 :用 t检验和卡方检验对各种因素进行统计学处理。结果 :初诊时外周血白细胞 (WBC) <2 0× 10 9/ L组和 WBC 2 0× 10 9/ L～ 5 0× 10 9/ L组分别与 WBC >5 0× 10 9/ L组比较 ,缓解率均有显著性差异 (P<0 .0 1和 P<0 .0 5 ) ;根据初诊时血清中乳酸脱氢酶 (L DH )值 ,将 CR组与 PR组、CR组与 NR组两两比较 ,均有显著性差异 (P<0 .0 1)。低年龄组 (16岁～ 5 5岁 )治疗缓解率 (6 7.1% )大于高年龄组 (>5 5岁 )缓解率 (6 0 .4% ) ;初诊时外周血及骨髓 (BM)中原始 +(早 )幼稚细胞比例数低者治疗缓解率高于比例数高者治疗缓解率 ,但均无显著性差异 (P>0 .0 5 )。结论 :患者年龄、初诊时 WBC、L DH、外周血及 BM中原始 +(早 )幼稚细胞比例数均为 ANL L治疗缓解率的相关因素。
Objective:To analyse the correlated factors of remission rate in newly diagnosed adult acute non lymphocytic leukemia patients.Methods:Statistical studies with t test and χ 2 test were used to analyse several correlated factors.Results:①The remission rate in patients with WBC <20×10 9/L and WBC 20×10 9/L～50×10 9/L was significantly higher than with those WBC>50×10 9/L( P <0.01 and P <0.05).②Serum LDH in CR group was significantly different with those in PR and NR groups ( P <0.01).③The remission rate in low aged group was 67.1 % (CR),which was higher than those in high aged group (60.4 %);and the patients with lower initial blasts and promyelocytes had higher remission rate than the others,but not reach significant difference ( P >0.05).Conclusion:The remission rate were correlated with age,WBC,LDH and blast cells in blood and bone marrow.
出处
《白血病．淋巴瘤》
CAS
2001年第4期228-229,共2页
Journal of Leukemia & Lymphoma
关键词
非淋巴细胞白血病
急性
治疗缓解率
相关因素
Non lymphocytic leukemia
Acute
Treatment remission rate
Correlated factor
