摘要
目的 探讨充血性心力衰竭 (CHF)患者血清肌酸激酶同功酶 (CK -MB)与肌酸激酶 (CK)比值 (B/K)的变化规律及其临床意义。方法 测定 93例不同病因所致的CHF患者和 45例同期非心血管病对照组患者及 16例心功能Ⅰ级患者的血清CK -MB、CK及B/K比值。结果 所有患者的CK -MB、CK均在正常值范围 ,随心功能不全的加重B/K比值逐渐升高 ,心功能Ⅳ级与对照组比较有非常显著性差异(P <0 0 1) ,心功能Ⅳ、Ⅲ级与心功能Ⅱ、Ⅰ级比较有非常显著性差异 (P <0 0 0 1)。
Objective To evaluate the clinical value of serum creatine kinase (CK) and ratio of CK-MB mass/CK-activity (B/K) in the patients with congestive heart failure (CHF). Methods CK and CK-MB were measured in 93 patients with CHF and 45 patients without cardiovascular disease. Result CK and CK-MB value of all patients were normal. The lower the cardiac function was, the higer the B/K value was. Ratio of B/K in the patients NYHA function class Ⅰ?Ⅱ?Ⅲ?Ⅳ were 0.09 ±0.03, 0.19±0.07, 0.25±0.10, 0.33±0.15, respectively. Control group was 0.23±0.16. There was a significant statistic difference between class Ⅳ group and control group ( P <0.01). Conclusion The ratio of CK-MB mass/CK-activity is an index of cardiac function in patients with CHF.
出处
《岭南心血管病杂志》
2001年第5期349-351,共3页
South China Journal of Cardiovascular Diseases
