摘要
目的 :对比分析 60岁以上与 4 0岁以下食管癌的临床特点及预后。方法 :1986年 11月～ 1992年 12月收治食管癌 663例 ,其中 60岁以上 (高龄组 )组 172例 ,4 0岁以下 (低龄组 ) 4 0例。高龄组平均就诊时间 3个月 ,病灶长度 >5cm者占 5 3.5 % ;低龄组平均就诊时间 2 .5个月 ,病灶长度 >5cm者占75 % ,两组比较差异有极显著性 (P <0 .0 1) ,两组发病部位、X线分型、病理类型大致相同。均采用6 0 Co外照射 ,总剂量DT60～ 70Gy。结果 :高龄组的 1、3、5年生存率分别为 5 4.7%、13.4 %、7.0 % ,放疗后远处器官转移率为 8.7% ;低龄组的 1、3、5年生存率分别为 4 7.5 %、12 .5 %、5 0 % ,放疗后远处器官转移率为 32 .5 % (P <0 .0 0 1)。结论 :60岁以上与 4 0岁以下食管癌放疗疗效相仿 ,但后者放疗后远处器官转移率高。
objective To analyze clinical characteristics and radiotherapeutic efficacy on patients with esophageal carcinoma aged between 40 years younger and 60 older.Methods From November 1986 to December 1992,663 patients were enrolled into the study and 172 patients were over 60 years old and 40 patients 40 years younger among them.The median time to receive irradiation was 3 months and 2.5 month for older group and younger group respectively.53.5 percent of patients had esophageal lesion longer than 5 cm in the older group,while 75% patients in the younger group ( P <0.05).All patients received external 60 Co irradiation,D T 60-70 Gy.Results The overall 1?3 and 5 year survival rate is 54.7%,13.4% and 7.0% in the older group and 47.5%,12.5% and 5.0% in the younger group;8.7% patients developed distant metastases after radiotherapy in the older and 32.5% in the younger group ( P <0.001).Conclusions The results of radiotherapy achieved in esophageal cancer patients of more than 60 year and less than 40-year were similar,but the latter had more distant organ metastasis rate.
出处
《肿瘤防治杂志》
2001年第5期506-507,共2页
China Journal of Cancer Prevention and Treatment
关键词
食管癌
放射疗法
预后
年龄
治疗
esophageal neoplasms
radiotherapy
prognosis
age
