摘要
目的:研究微电极放大器中的50Hz滤波电路对心肌细胞自发动作电位波形及各项参数的影响。方法:将心肌细胞自发动作电位经玻璃微电极、微电极放大器、微分器、A/D转换器输入微型计算机。在应用和不应用微电极放大器中50Hz滤波功能两种情况下,对心肌细胞自发动作电位波形进行比较分析。结果:在使用微电极放大器中50Hz滤波功能情况下,动作电位波形在0相严重失真,时程延长,除极化最大速度减小;复极化50％、90％的时间延长;其它参数无显著变化。结论:心肌细胞动作电位波形中含有50Hz信号成分,在研究心肌细胞动作电位信号时,不能使用50Hz滤波器。如果使用50Hz滤波器,会造成动作电位波形严重失真,影响实验结果。
Objective: To study the effects of the 50 Hz-filter circuit in a microelectrode amplifier on spontaneous cardiac action potential waveform and parameters. Methods: Spontaneous cardiac action potential signals were fed into a microcomputer through a glass microelectrode, a microelectrode amplifier, a differentiator and A/D converter. The cardiac action potential signals were recorded and analyzed with 50 Hz-filter circuit and without it. Results: When the 50 Hz-filter circuit was used, the phase 0 in the potential waveform was seriously distorted and its duration was prolonged. The maximal rate of depolarization at the phase 0 was decreased. The duration of 50% repolarization and the duration of 90% repolarization were prolonged. The other parameters were not effected. Conclusion: There has already been 50 Hz element in the action potential waveform. During amplifying the cardiac action potential signal, the 50 Hz-filter circuit should not be turned on. Otherwise, the experiment results will be effected.
出处
《中国医学物理学杂志》
CSCD
2001年第3期151-152,共2页
Chinese Journal of Medical Physics
关键词
心肌细胞动作电位
干扰
50Hz滤波
信号分析
cardiac action potential
interference
50Hz-filter circuit
signal analyzing
