摘要
目的:探讨结石在胆囊息肉样病变中的高危因素。方法:将72例胆囊息肉样病变(PLG)按是否合并结石分为A(合并结石组)、B(不合并结石组)两组。分析其临床病理特征,应用光镜观察胆囊粘膜上皮肠化生,不典型增生的发生率。结果:①72例PLG中发现胆囊粘膜上皮轻、中、重度不典型增生,肠化生共计17例。包括胆囊癌7例,腺瘤性息肉3例,肌腺瘤2例,胆固醇息肉5例。②A组26例中发现上述病理损害12例,占46％。B组46例中5例,占11％。经统计学处理,A、B两组间存在显著性差异(P<0.01)。结论:结石及其重复炎症反应对PLG是肿瘤高危因素。
Objective:To determine if calculus is a high-risk factor in polypoid lesion of the gallbladder. Methods: Tlcases of cholecystic polypoid lesion were divided into A (complicated gallstone group) and B(gallstonefree group)according to complicated or uncomplicated calculus. Clinical features and pathologic characters were analysed. The incidences of the cholecystic mucosal epithelial intestinal metaplasia and atypical hyperplasia were observed with microscope.Results:(1)Within 72 cases of cholecystic polypoid lesion it was found that 17 cases of cholecystic mucosal epithelium had low,middle or grave degree atypical hyperplasia or intestinal metaplasi-a, including 7 cases of cholecystic carcinoma,3 cases of adenomatous polypus,2 cases of adenomyoma ,5 cases of cholesterol polyp.(2) In group A 12 cases(46%) were found as pathologic lesion above-mentioned.However,there were only 5 cases (11%) of group B with the lesion. Statistical analysis results showed, there were obvious differences between group A and group B( P < 0.01). Conclusion: The calculus and often-repeated inflammatory reaction were high-risk factors of the tumorous cholecystic polypoid lesion.
出处
《医学理论与实践》
2001年第10期978-979,共2页
The Journal of Medical Theory and Practice
