摘要
目的 :探讨有创机械通气治疗各种严重呼吸衰竭的最佳时机。 方法 :分析 14例常规药物与氧疗无效而接受有创机械通气治疗 (经口或经鼻气管插管 )的呼吸衰竭患者的临床资料 ,依据转归分为痊愈与病死两组 ,每组各 7例 ,分别比较年龄、入住 RICU时的一般情况、机械通气治疗时临床指标 ,结合呼吸衰竭确诊至机械通气治疗间隔时间 ,综合评价有创机械通气治疗时机与转归之间关系。 结果 :痊愈组年龄显著轻于病死组 (P<0 .0 5 ) ,分别为 (5 6 .5 7± 11.87)岁、(78.71± 10 .75 )岁 ;呼吸衰竭确诊至应用机械通气治疗间隔时间痊愈组显著短于病死组 (P<0 .0 5 ) ,分别为 (15 .14± 11.38) h、(71.5 7± 48.34) h;此外 ,痊愈组机械通气治疗时间显著短于病死组 (P<0 .0 5 ) ,分别为 (0 .2 9± 8.96 ) d、(31.5± 14.41) d;VAP与 MODS发生率两组分别为 14.3%、71.4%和 2 8.6 %、85 .7%。结论 :虽然接受机械通气治疗患者的预后受多种因素影响 ,但获得有效机械通气治疗的时机也是不可忽视的环节。对经积极内科保守治疗无法缓解的呼吸衰竭患者 ,应不失时机地应用机械通气治疗。
Objective:To discuss the optimal time for invasive mechanical ventilation (MV) in various severe respiratory failure.Methods:Fourteen intruded patients with severe respiratory failure inefficient to medicine and oxygenic treatment were observed.They were divided into recovered group and death group according to the prognosis.Age,duration of ventilation and survival,incidence of ventilator-associated pneumonia (VAP) and multiple organ dysfunction syndrome (MODS) were analyzed between 2 groups.Results: Between recovered group and death group,age was (56.57±11.87)years vs (70.71± 10.75) years, P <0.05. The duration from comfirmation of respiratory failure to MV treatment was (15.14±11.38) h vs (71.57±48.34) h in revovered group and death group,respectively, P <0.05;the duration of ventilation was (10.29± 8.96) d vs (31.5± 14.41) d; P <0.05,respectively.The incidence of VAP was 1/7 vs 5/7;MODS was 2/7 vs 6/7.Conclusion:The optimal opportunity of MV is very important and it can obtain better prognosis to exacerbated respiratory failure.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2001年第9期889-890,共2页
Academic Journal of Second Military Medical University
