摘要
目的 :探讨 α1 A受体阻滞剂盐酸坦索罗辛治疗慢性前列腺炎的疗效与机制。方法 :6 4例慢性前列腺炎患者被随机分为两组 ,实验组口服盐酸坦索罗辛及左旋氧氟沙星 ,对照组仅口服左旋氧氟沙星 ,均治疗 6周。结果 :实验组较对照组在前列腺炎症状评分 (P <0 .0 5 )及最大尿流率方面 (P <0 .0 1)均有较大改善。前列腺液中WBC下降率两组差异无显著性意义 (P >0 .0 5 )。结论 :盐酸坦索罗辛可松弛前列腺部尿道平滑肌 ,降低后尿道压力 ,缓解尿液前列腺反流 ,改善慢性前列腺炎症状。
Purpose:To study the effect and mechanism of α 1A blockers in the treatment of chronic prostatitis.Methods:64 outpatients were randomly divided into two groups. The treated group patients were treated with α 1A blockers(Harnel)and antibiotics, the control group patients were treated only with antibiotics. The treatment period was 6 weeks.Result:In α 1A blocker treated group, the symptomatic score (SFQ) and the maximum flow rate (MFR) were significantly improved in comparison with controls, but the leucocyte (WBC) counting had no significant changes.Conclusion:α 1A blockers can reduce the rear urethral pressure, relief the intraprostatic urinary reflux and improve the symptoms of chronic prostatitis.
出处
《临床泌尿外科杂志》
2001年第9期408-409,共2页
Journal of Clinical Urology
