摘要
用高效毛细管电泳 (HPCE)和高效液相色谱 (HPL C)两种方法 ,对青霉素 V的发酵过程及提炼过程进行了跟踪检测 ,找到了青霉素 V及相关物质的变化规律 ,为实际生产中发酵效价和提炼收率的提高 。
By high performance capillary electrophoresis (HPCE) and high performance liquid chromatography (HPLC), penicillin V and related substances were analysed and determinated in the process of fermentation and extraction. The changing of profiles penicillin V and related substances in the process was elucidated. The result is useful in monitoring and also the process control for increasing the productivity of fermentation and recovery rate of extraction.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2001年第4期250-253,共4页
Chinese Journal of Antibiotics
