摘要
对 4例海洛因成瘾死亡者胰腺的超微病理改变进行了研究 .研究发现 ,胰腺腺泡上皮细胞线粒体不同程度肿胀、嵴断裂 ,粗面内质网丰富、扩张、分泌颗粒减少 ,可见多量聚集成堆的酶原颗粒 ;胰岛细胞粗面内质网丰富 ,线粒体丰富 ,神经内分泌颗粒丰富 ,小部分细胞神经内分泌颗粒减少 .说明海洛因对胰腺超微结构影响显著 .
Research on heroin-addicts′ pancreas in 4 cases by TEM showed that mitochondria epithelial cells in pancreatic acinus swell to varying degrees with hypertrophic and dilated rough surfaced endoplasmic reticulum,and decreased secretory granules resulting in a great number of visible zymogen granules in heaps; and that rough surfaced endoplasmic reticulum in pancreatic islet cells were many and had dilated with hyperplasia mitochondrion,rich neuroendocrine granules and a small part of reduced ones. The results reveal that heroin brings about remarkable injury in ultrastructural pathology of pancreata
出处
《昆明医学院学报》
2001年第3期1-3,共3页
Journal of Kunming Medical College
基金
国家自然科学基金资助 ( 3 9760 0 76)
关键词
海洛因成瘾
胰腺
超微结构
透射电镜
Heroin-addicts
Pancreas
Ultrastructure
Transmission Electron Microscope (TEM )
