摘要
目的 :评价甲孕酮对乳腺癌患者化疗期间生活质量的影响。方法 :对62例住院化疗的乳腺癌患者随机分为甲孕酮(MPA)组和对照组(服淀粉片) ,根据KPS评分进行双盲回顾性分析。结果 :MPA组综合指数KPS评分(86.7 %)较对照组(33.3%)明显提高(p<0.01) ;伴有骨转移的晚期患者癌痛缓解率 ,治疗组为83.3 % ,对照组为50 %。结论 :甲孕酮可显著改善乳腺癌患者化疗期间的生活质量。
Objective:To evaluate the effect of MPA on the life quatity of patients with breast cancer during chemotherapy.Methods & Materials:Sixty-two patients receiving chemotherapy were devided into two groups randomizedly.Group I:32 patients were administered with MPA during chemotherapy.Group Ⅱ:30 cases received the same chemotherapy without MPA administration as the control group.The life quality of both groups of patients was retrospectively analyzed according to Karnofsky's Performance Score System(KPs).Results:The comprehensive index of life quality according to the KPS in Group I was remarkablely higher(86.7% versus Group Ⅱ of 33.3%, P<0.01),83.3% of patients in Group Ⅰ with complaint of pain had relieved in contrast to 50% in Group Ⅱ.Conclusion:Our results show that MPA may be used for breast cancer patients to improving their life quality during chemotherapy.
出处
《四川肿瘤防治》
2001年第3期146-147,共2页
Sichuan Journal of Cancer Control
关键词
甲孕酮
乳腺癌
化疗
生活质量
治疗
Medroxyprogesterone Acedate
Breast cancer
Chemotherapy
Life quality
