摘要
目的 :观察干扰素α 2a治疗腺病毒肺炎疗效。方法 :将 60例患儿随机分为两组各 3 0例 ,均给予抗生素治疗外 ,治疗组给予干扰素α 2a 5～ 10万U·kg 1·d 1,im ,对照组加阿昔洛韦 10mg·kg 1·d 1,静脉滴注 ,疗程 4～ 6d。结果 :治疗组退热时间、临床症状、体征消失时间均优于对照组 ,病程缩短 1～ 4d。结论 :干扰素α 2a治疗腺病毒肺炎 ,可抑制细胞内病毒的繁殖 。
Objective:To investigate the therapeutic effects of recombinant interferon α 2a on adenovirus pneumonia. Methods:60 children with adenovirus pneumonia admitted to the hospital during the period of August 1998 to August 2000 were randomly divided into two groups: the control group and the experiment group. All the cases in the two groups were treated with administration of antibiotics. Meanwhile, the patients in the experiment group were also given recombinant interferon α 2a intramuscularly with a dose of 50,000 100,000 U·kg 1 .day and those in the control group were also treated by intravenous drip of acyclivir with a dose of 10 mg·kg 1 .day. The treatment lasted for a session of 4 to 6 days. Results:It was showed that time for relief of fever and control of clinical manifestations in the experiment group was significantly shorter than that in the control group. Conclusion:Recombinant interferon α 2a can shorten the length of adenovirus pneumonia in children by inhibiting virus replication in the virus infected cells.
出处
《医药导报》
CAS
2001年第9期572-572,共1页
Herald of Medicine
