摘要
目的 检测肾综合征出血热患者尿液中特异性IgM抗体 ,研究早期诊断方法。 方法 :用MacELISA法检测不同病日HFRS病人尿液中特异性IgM抗体。 结果 :HFRS病人尿夜中特异性IgM抗体总阳性率为 76.4 7% ,第 3病日即可出现阳性 ,7- 9病日阳性率可达 83 .87% ,与同期HFRS病人血清抗体检测对比无显著性差异 (P >0 .0 5 )。结论 :用MacELISA检测HFRS尿液中特异性IgM抗体敏感性高 ,特异性强 ,适合早期诊断。
Aim To detect IgM (SIgM) antibodies in urinary specimens of patients with hemorrhagic fever with renal syndrome (HFRS) and study the methods for early diagnosis.Methods The SIgM Antibodies of patients with HFRS in various illness days were detected by IgM antibody capture ELISA (Mac ELISA) technique. Results The SIgM antibodies positive urine specimens occurred on day 3 of illness. The total positive rate and the positive rate from day 7 to day 9 of illness were 76.47% and 83.87% respectively (P>0 05 as compared with detection of serum SIgM antibodies).Conclusion High specialization and sensitivity were observed by Mac ELISA for detection of urinary SIgM antibody in HFRS. That will be for early diagnosis.
出处
《中国人兽共患病杂志》
CSCD
北大核心
2001年第5期89-90,共2页
Chinese Journal of Zoonoses
基金
温州医学院附属第一医院医药科学基金资助 (编号 :96-1618)
