摘要
目的 为了探讨慢性肾功能不全患者合并消化道出血的高危因素及早期预防、治疗的方法。方法 对 35例临床确诊的该类病人结合文献进行回顾性分析。结果 11例于出血后 3d死亡。年龄、血浆蛋白、血尿素氮、血肌酸酐、血钙及血磷水平 ,红细胞压积 ,胸部平片 ,出血时间及营养状况均有有意义的改变。消化道出血前 94%病人透析抗凝剂均选用普通肝素。结论 通过分析发现高龄、贫血、低钙、高磷、营养不良、凝血机制障碍、心肺疾患、普通肝素的应用、透析不充分、NO合成抑制、血浆胃泌素水平增高等因素是合并消化道出血的危险因素 ,同时我们应建立该并发症的急、危、重症概念。
Objective To explore high risk factors of the patients with chronic renal failure(CRF)associated with digestive system bleeding,and early prevention and treatment for those patients.Methods Retrospectively analysed the date of above 35 confirmed clinically diagnosed patients,in combination with review of relative literature.Results Eleven of the 35 patients died 3 days after bleeding.The calcium and phosphorous,and hematocrit,X chest film,bleeding time of the patients and their age and nutritional status had significant changes.Before digestive system bleeding 94% of the patients selectively used ordinary heparin as anticoagulants of dialysis.Conclusion It is found that aged,anemia,low content of calcium,high content of phosphorous,nutrition insufficiency,coagulation dysfunction,disorders of heart and lung,use of ordinary heparin,dialysis insufficiency,NO synthesis inhibition,and increased level of plasma gastrin are risk factors associated bleeding of CRF.Also authors believes that the establishment of concepts on acute,severe,critical disorders of the complication is in need. [
出处
《前卫医药杂志》
2001年第2期93-95,共3页
Qianwei Journal of Medicine & Pharmacy
