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龈下菌斑中肽酶活性和龈沟液中碱性磷酸酶水平相关性的研究 被引量:1

The study of the correlation between peptidase activity in subgingival plaque and alkaline phosphatase in gingival crevicular fluid.
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摘要 目的 :探讨成人牙周炎龈下菌斑中三种牙周致病菌产生的肽酶高低与龈沟液中碱性磷酸酶水平的相关性及其在牙周炎活动性诊断中的意义。方法 :利用Periocheck椅旁快速检测 6 0例成人牙周炎患者共 72个位点、15例健康对照 15个位点龈下菌斑中肽酶活性 ,同时测量龈沟液中ALP水平。结果 :成人牙周炎患者肽酶活性、ALP水平显著高于健康对照组 ,并与探诊深度、附着丧失、牙龈指数呈正相关关系 ,同时二者之间具有一定的相关性。结论 :龈下菌斑肽酶活性和龈沟液中ALP水平相关 ,二者均反映牙周炎的严重程度 。 Objective:To observe the possible correlation between t he peptidase activity produced by three periodontal bacteria in subgingival plaque and alkaline phosphatase (ALP) in gingival crevicular fluid (GCF) in adult periodontitis and evaluate the diagnostic value of two methods for the activity of periodontitis.Method:to measure 72 sites in 60 adult periodontitis patients peptidase activity in subgingival plaque by Periocheck chair-side rapid diagnosis and ALP levels in GCF by automatic analysis.Result:Peptidase activity and ALP levels were much higher in adult periodontitis patients than those in healthy controls.Both the peptidase activity and ALP level were significantly correlated with clinical parameters such as PD?CAL and GI.Peptidase activity and ALP levels ware found to have significantly positive correlation with each other.Conclusion:These results indicate that peptidase activity in subgingival plaque and ALP levels in GCF may be considered as potential markers for the activity of periodontitis.
出处 《口腔医学纵横》 CSCD 2001年第3期183-185,共3页 Journal of Comprehensive Stomatology
关键词 肽酶 椅旁快速检测 龈沟液 碱性磷酸酶 牙周炎 peptidase activity Periocheck ALP-GCF periodontitis
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