摘要
目的 探讨双相气道正压 (BIPAP)通气模式治疗急性呼吸窘迫综合征 (ARDS)的疗效。 方法 将 2 0例ARDS患者随机分为BIPAP组和间歇性正压通气 (IPPV)组行机械通气治疗 ,每组 10例。观察机械通气期间患者镇静剂和肌肉松弛剂用量 ,气道力学参数中吸气峰压 (PIP)、平台压 (Pplate)和呼气末正压 (PEEP)的变化以及机械通气的时间。 结果 15例 (75 % )治愈出院 ,5例死亡。BIPAP组机械通气时间 [(13± 7.5 )d]显著低于IPPV组 [(2 1± 11.6 )d](P <0 .0 5 )。BIPAP组安定、吗啡和万可松用量显著低于IPPV组 (P <0 .0 5 ) ;IPPV组PIP、Pplate和PEEP均显著高于BIPAP组 (P <0 .0 5 )。 结论 BIPAP通气模式人机关系协同性好 。
Objective To evaluate the effect of biphasic positive airway pressure (BIPAP) mechanical ventilation mode on acute respiratory distress syndrome (ARDS) and compare it with intermittent positive pressure ventilation (IPPV). Methods Twenty ARDS patients were randomly divided into a BIPAP group and an IPPV group (n= 10 in each group). Blood gas analysis and respiratory mechanics were monitored. Results Fifteen (75%) patients were discharged from the hospital, 5 died of multiple organ failure. In the BIPAP group, the total duration of mechanical ventilation was 13±7.5 days, which was significantly less than that (21±11.6 days) in the IPPV group ( P <0.05). The dosage of valium, morphinum and vecuronium used during mechanical ventilation was significantly greater in the IPPV group than in the BIPAP group ( P <0.05). Peak inspiratory pressure, plateau pressure and PEEP were significantly higher in the IPPV group than in the BIPAP group ( P <0.05). No significant difference in PaO 2 and pH was found between the two modes. Conclusions BIPAP is an effective mode of mechanical ventilation therapy for ARDS patients. It shortens the duration of mechanical ventilation.
出处
《中华创伤杂志》
CAS
CSCD
北大核心
2001年第8期472-474,共3页
Chinese Journal of Trauma
关键词
间歇正压通气
急性呼吸窘迫综合征
双相气道正压通气
治疗
Intermittent positive pressure ventilation
Acute respiratory distress syndrome
Biphasic positive airway pressure ventilation
