摘要
目的 探讨羊膜移植 (am niotic mem brane trans-plantation,AMT)在难治性角膜溃疡中的治疗效果。方法 各种病因的难治性角膜溃疡共 17眼 ,其中真菌感染 3眼 ,病毒感染 3眼 ,细菌感染 5眼 ,病原体不明者 6眼 ,经相应抗感染药物治疗病情未控制 ,或角膜溃疡经久不愈 ,对角膜溃疡位于浅层 1/ 3基质以内者 ,刮除角膜上皮细胞及坏死组织 ,行单层羊膜覆盖术 ;对于溃疡达 1/ 3基质以上者 ,行病灶板层角膜切除 ,双层或多层羊膜垫塞联合单层羊膜覆盖术。术后继续应用相应抗感染治疗。结果 全部患者角膜感染于术后 5～ 10 d控制 ,角膜溃疡于术后 2周内愈合 ,4眼角膜透明 ,12眼溃疡区瘢痕愈合 ,遗留瘢翳 ,裸眼视力 0 .3～ 0 .8者7眼 ,手动～ 0 .1者 10眼。结论 用人羊膜移植治疗药物难以控制的浅。
Objective To evaluate the therapeutic effects of amniotic membrane transplantation (AMT) in corneal ulcer refractory to conventional treatment.Methods Three eyes of fungal corneal ulcer, 3 eyes of herpes simplex keratitis, 5 eyes of bacterial corneal ulcer and 6 eyes of corneal ulcer without specific microorganism were treated with AMT. The procedure included monolayer amniotic membrane patch and focus lamellar keratectomy with multilayer AMT.Results The infection and inflammation was controlled within 10 days. There were corneal transparency in 4 eyes, corneal macula in 12 eyes .The uncorrected visual acuity was from 0.3 to 0.8 in 7 eyes and handmoving to 0.1 in 10 eyes.Conclusion The transplantation of preserved amniotic membrane is a valuable method for the treatment of refractory corneal ulcer.
出处
《眼科新进展》
CAS
2001年第4期252-254,共3页
Recent Advances in Ophthalmology
关键词
难治性角膜溃疡
羊膜移植
AMT
corneal ulcer
refractory
amniotic membrane transplantation
